Oxytocin response to food intake in avoidant/restrictive food intake disorder
Authors' conclusion
Consistently high oxytocin levels might be involved in low appetite and sensory aversions to food, contributing to food avoidance in individuals with ARFID.
Study context
- Population
- Adolescents and young adults with ARFID vs healthy controls, given a ∼400-kcal standardized mixed meal
- Participants
- 109 adolescents
- Exposure
- ARFID vs healthy controls
- ARFIDn = 54
- Healthy controls (HC)n = 55reference
- Outcome
- Mean serum oxytocin levels across time points (fasting and 30-, 60-, 120-min postmeal)
- Follow-up
- Fasting and 30-, 60-, and 120-min postmeal
Main finding
As reported in the abstract
Mean oxytocin levels · all time points
- ARFID had greater mean oxytocin levels at all time points vs HC
- ARFID vs HC: P = 0.004
Observational data: associations, not effects.
Further findings
Impact of clinical variables (sex, age, BMI percentile) on oxytocin in ARFID · fasting and postprandial
- Sex, age and BMI percentile showed no impact on fasting and postprandial oxytocin levels in ARFID
Original publication
Oxytocin response to food intake in avoidant/restrictive food intake disorder. Eur J Endocrinol. Published 20 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →