Etiology, morphology, and outcomes of adrenal calcifications in 540 adult patients—a retrospective single-center study
Authors' conclusion
In summary, adrenal calcifications are usually incidentally discovered unilateral, punctate, or coarse lesions of unclear etiology. Most calcified adrenal tumors are benign and <20% malignant or pheochromocytomas.
Study context
- Population
- Adults with adrenal calcification on CT, December 2017 to January 2021; median age 65 years, 45% women
- Participants
- 540 consecutive patients
- Outcome
- Etiology and morphology of adrenal calcification
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
- Discovered incidentally
- 472, 87%
- Etiology: idiopathic
- 389, 72%
- Etiology: adrenal tumor
- 113, 21%
- Etiology: hemorrhage
- 29, 5%
- Etiology: infiltrative disease
- 7, 1%
- Calcified adrenal tumors benign
- 92, 81%
- Benign calcified tumors that were adenomas
- 63, 69%
- Calcified adrenal malignancy
- 16, 18%
- Malignancies that were metastasis
- 12, 67%
- Calcification unilateral
- 94%
- Calcification bilateral
- 6%
- Morphology punctate
- 313, 58%
- Morphology coarse
- 165, 30%
- Morphology linear/curvilinear
- 46, 9%
- Morphology rim-like
- 16, 3%
Observational data: associations, not effects.
Original publication
Etiology, morphology, and outcomes of adrenal calcifications in 540 adult patients—a retrospective single-center study. Eur J Endocrinol. Published 20 July 2023. doi:10.
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