Optimizing frozen section sampling for thyroid follicular neoplasms through intraoperative ultrasound guidance
Authors' conclusion
Intraoperative high-frequency ultrasonography can effectively identify abnormalities in tumor capsular continuity, guide optimized sampling for intraoperative frozen section analysis, significantly improve the intraoperative detection of malignant tumors, and provide reliable intraoperative guidance.
Study context
- Population
- Patients scheduled for surgical resection for thyroid follicular neoplasms
- Participants
- 248 patients
- Comparison
- Intraoperative high-frequency US-guided frozen section sampling vs control
- Experimentaln = 118
- Controln = 130reference
- Primary endpoint
- Diagnostic accuracy of intraoperative frozen section pathology vs permanent histopathology (gold standard)
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
Diagnostic accuracy of intraoperative frozen section pathology
P < 0.05
Original publication
Optimizing frozen section sampling for thyroid follicular neoplasms through intraoperative ultrasound guidance. Eur Thyroid J. Published 24 June 2026. doi:10.
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