One-year real-world benefits of Tandem Control-IQ technology on glucose management and person-reported outcomes in adults with type 1 diabetes: a prospective observational cohort study
Authors' conclusion
One-year use of Control-IQ was associated with better glucose management, improved diabetes-related quality of life, more treatment satisfaction, less severe hypoglycaemia and less work absenteeism in adults with type 1 diabetes.
Study context
- Population
- Adults with T1D starting Control-IQ (Dec 2021–Dec 2022), 13 Belgian diabetes centres; mean age 38.5 ± 13.1 years, 57.3% female
- Participants
- 473 adults
- Exposure
- Control-IQ at start vs after 12 months
- Outcome
- Evolution of TIR (glucose 3.9-10.0 mmol/l)
- Follow-up
- 12 months
Methodological detailsmulticentre, real-world, Data collected at start and after 4, 8 and 12 months, Data reported as mean ± SD or least-squares mean (95% CI)
- Multicentre
- Real-world
- Data collected at start and after 4, 8 and 12 months
- Data reported as mean ± SD or least-squares mean (95% CI)
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
HbA1c · 12 months · decreased
P < 0.001
HbA1c % Start 7.4% [7.3, 7.5] · 12 months 6.7% [6.6, 6.8]
| Outcome | Start | 12 months | P value |
|---|---|---|---|
| Time <3.9 mmol/l · 12 monthsDecreased | 4.2% (CI 3.9–4.6) | 1.9% (CI 1.8–2.1) | P < 0.001 |
- Hypoglycaemia Fear Survey v2 worry · better scores
- P < 0.001
- Problem Areas in Diabetes - Short Form · better scores
- P < 0.001
- Diabetes Treatment Satisfaction Questionnaire status · better scores
- P < 0.001
- Work absenteeism days · decreased
- P = 0.034
Hypoglycaemia Fear Survey v2 worry
- Scores (22.5 [21.3, 23.7] vs 18.1 points [17.0, 19.3])
Problem Areas in Diabetes - Short Form
- Scores (7.2 [6.7, 7.8] vs 6.1 points [5.5, 6.7])
Diabetes Treatment Satisfaction Questionnaire status
- Scores (25.5 [24.8, 26.2] vs 31.0 points [30.4, 31.6])
Work absenteeism days
- Days per 100 person-years (116.3 [42.8, 315.5] vs 69.3 [25.4, 189.2])
Safety
| Outcome | P value |
|---|---|
| Self-reported severe hypoglycaemia events12 months vs Start · decreased | P = 0.002 |
Self-reported severe hypoglycaemia events
- Events per 100 person-years (37.5 [21.3, 65.9] vs 15.7 [9.7, 25.3])
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →