Gestational diabetes & diabetes in pregnancy
One‐year postpartum weight retention and glucose intolerance in women with prediabetes after gestational diabetes
Authors' conclusion
In women with a previous history of GDM and prediabetes in early postpartum, PPWR in early postpartum was a strong independent predictor for late PPWR, while earlier start of insulin therapy during pregnancy and delivery by caesarean section were independent predictors of glucose intolerance in late postpartum.
Study context
- Population
- Women with prediabetes at the 6–16 weeks postpartum OGTT after a recent history of GDM
- Participants
- 167 women
- Comparison
- PPWR vs no PPWR at 1-year postpartum
- PPWRn = 75
- Primary endpoint
- Risk factors for PPWR and glucose intolerance (prediabetes + diabetes)
- Follow-up
- 1-year postpartum
Methodological detailsexploratory analysis
- Exploratory analysis
Primary result
As reported in the abstract
- PPWR >0 kg
- 45% (75)
- Only independent predictor of late PPWR: weight retention in early postpartum
- p < 0.001
- Glucose intolerance (84 prediabetes, 8 diabetes)
- 55.1% (92)
Further findings
Gestational weight gain · higher with PPWR
P < 0.001
Metabolic syndrome
P = 0.003
BMI and metabolic profile (waist circumference, lipids, insulin resistance), early and late postpartum
- Higher BMI with PPWR
- P < 0.01
- Worse metabolic profile with PPWR
- all p < 0.05
Original publication
One‐year postpartum weight retention and glucose intolerance in women with prediabetes after gestational diabetes. Diabet Med. Published 3 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →