Obesity

Obesity mortality on the rise: A 54‐year US perspective

Diabetes Obes MetabPublished Population-based descriptive study

Authors' conclusion

After a decline from 1968 to 1985, obesity AAMRs rose until 2019, and spiked during the pandemic, reaching their highest recorded level in 2021. Disparities persist across sex, race, and geography, warranting targeted public health strategies.

Study context

Population
US individuals aged ≥25 years with obesity recorded as underlying cause of death (ICD codes), 1968–2021
Participants
174,625 obesity deaths
Outcome
Obesity AAMRs per 100 000 individuals
Follow-up
1968–2021
Methodological detailsJoinpoint regression, CDC WONDER national mortality data
  • Joinpoint regression
  • CDC WONDER national mortality data

Main finding

As reported in the abstract

Obesity AAMR per 100 000

AAMR in 1968

1.15

95% CI 1.09–1.22

AAMR in 2019

3.39

95% CI 3.31–3.46

AAMR in 2021

4.54

95% CI 4.45–4.62

Observational data: associations, not effects.

Further findings

Sex disparities

Males had higher age-adjusted mortality rates (AAMRs) than females during the latter part of the study period

Racial disparities

Black or African American individuals had higher AAMRs than White individuals during the study period

State obesity mortality rates · 1999–2019

Lowest: Hawaii
1.62 (95% CI: 1.44-1.80)
Highest: West Virginia
4.46 (95% CI: 4.21-4.72)

Original publication

Obesity mortality on the rise: A 54‐year US perspective. Diabetes Obes Metab. Published 1 December 2025. doi:10.1111/dom.70342

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