Obesity

Multidimensional Analysis of Early Adiposity Rebound Determinants in Children: Two Key “1000 Days”

Obesity (Silver Spring)Published Prospective birth cohort study with machine learning prediction modelling

Study context

Population
Parent-offspring trios in the Ma'anshan Birth Cohort (MABC), serial BMI from birth through school age; early adiposity rebound (early AR (EAR)) = adiposity rebound (AR) timing ≤ sex-specific 25th percentile (≤ 55.46 months in boys, ≤ 60.54 months in girls)
Participants
2,072 parent-offspring trios
Outcome
Determinants of early adiposity rebound (EAR) and a predictive model
Methodological detailsMa'anshan Birth Cohort, linear mixed models for individual growth curves, 10 machine learning techniques and SHAP, 65 potential factors from maternal, pregnancy, paternal and offspring sources
  • Ma'anshan Birth Cohort
  • Linear mixed models for individual growth curves
  • 10 machine learning techniques and SHAP
  • 65 potential factors from maternal, pregnancy, paternal and offspring sources

Main finding

As reported in the abstract

Categorical boosting model (best of 10 ML models), AUC training

0.764

95% CI 0.733–0.795

Categorical boosting model, AUC testing

0.721

95% CI 0.669–0.773

Observational data: associations, not effects.

Original publication

Multidimensional Analysis of Early Adiposity Rebound Determinants in Children: Two Key “1000 Days”. Obesity (Silver Spring). Published 19 August 2026. doi:10.1002/oby.70278

Composed by AI from the published abstract and checked against it. How Briefs are made →

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