Mortality following proximal humerus fracture—a nationwide register study of 147,692 fracture patients in Sweden

Osteoporos IntPublished Nationwide register-based cohort study

Authors' conclusion

The mortality rate and SMR suggest that PHF patients are heterogeneous. Some older PHF patients may benefit from specialized care (e.g., orthogeriatric), and this should be evaluated in future studies.

Study context

Population
All adults (≥18 years) with proximal humerus fractures (PHF) in the Swedish Hospital Discharge Register, 2001–2016; mean age 69 years (range 18–111), male to female ratio 1:3; 86% treated non-surgically
Participants
147,692 adults
Exposure
PHF patients vs age- and sex-matched general population
  • PHFn = 147,692
Outcome
Mortality (crude mortality rate and SMR vs age- and sex-matched population)
Methodological detailspopulation-based comparison with age- and sex-matched mortality data, Data from Swedish Hospital Discharge Register and Swedish Cause of Death Register
  • Population-based comparison with age- and sex-matched mortality data
  • Data from Swedish Hospital Discharge Register and Swedish Cause of Death Register

Main finding

As reported in the abstract

Crude mortality rate after PHF
Crude mortality at 1 month
2.2%
Crude mortality at 3 months
4.1%
Crude mortality at 12 months
8.5%
Crude mortality at 48 months
24%
Age-adjusted standardized mortality rate (SMR), whole adult PHF population
3.9

Observational data: associations, not effects.

Further findings

SMR, 18–39 years
5.4
SMR, 40–64 years
3.9
SMR, 65–79 years
1.8
SMR, ≥80 years
1.2
Mortality increased with age; SMR highest among young patients

Original publication

Mortality following proximal humerus fracture—a nationwide register study of 147,692 fracture patients in Sweden. Osteoporos Int. Published 26 November 2022. doi:10.1007/s00198-022-06612-7

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