Modified American College of Radiology Thyroid Imaging Reporting and Data System and Modified Artificial Intelligence Thyroid Imaging Reporting and Data System for Thyroid Nodules: A Multicenter Retrospective Study
Authors' conclusion
The revised FNA thresholds and the stratification criteria of the mACR TI-RADS and mAI TI-RADS may be associated with improvements in specificity and accuracy, without significantly sacrificing sensitivity for malignancy detection.
Study context
- Population
- Thyroid nodules on US with definite pathological diagnoses, 6 Chinese hospitals, January 2017 to September 2021nodules in 2511 patients
- Participants
- 2,596 participants
- Comparison
- Modified American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS) and modified artificial intelligence (AI) TI-RADS vs original ACR TI-RADS
- Outcome
- Diagnostic performance and unnecessary FNA rate (UFR)
Methodological detailsmulticentre, retrospective
- Multicentre
- Retrospective
Performance
As reported in the abstract
| Test or model | Specificity | Accuracy | AUC | Unnecessary FNA rate (UFR) | Sensitivity |
|---|---|---|---|---|---|
| Modified ACR (mACR) TI-RADS | 73% | 74% | 0.80 | 25% | 87% |
| Modified AI (mAI) TI-RADS | 73% | 75% | 0.81 | 24% | 89% |
| Original ACR TI-RADS | 46% | 51% | 0.70 | 48% | 93% |
Specificity
Modified ACR (mACR) TI-RADS73%
Modified AI (mAI) TI-RADS73%
Original ACR TI-RADS46%
Accuracy
Modified ACR (mACR) TI-RADS74%
Modified AI (mAI) TI-RADS75%
Original ACR TI-RADS51%
AUC
Modified ACR (mACR) TI-RADS0.80
Modified AI (mAI) TI-RADS0.81
Original ACR TI-RADS0.70
Unnecessary FNA rate (UFR)
Modified ACR (mACR) TI-RADS25%
Modified AI (mAI) TI-RADS24%
Original ACR TI-RADS48%
Sensitivity
Modified ACR (mACR) TI-RADS87%
Modified AI (mAI) TI-RADS89%
Original ACR TI-RADS93%
- mACR TI-RADS vs Original ACR TI-RADS: all p < 0.001 — higher specificity, accuracy, AUC; lower UFR with mACR
- mACR TI-RADS vs Original ACR TI-RADS: P = 0.057 — slightly decreased with mACR
- mAI TI-RADS vs Original ACR TI-RADS: all p < 0.001 — higher specificity, accuracy, AUC; lower UFR with mAI
- mAI TI-RADS vs Original ACR TI-RADS: P = 0.13 — tended to be slightly decreased with mAI
- Between mACR TI-RADS and mAI TI-RADS: all p > 0.05 — no significant difference
Original publication
Modified American College of Radiology Thyroid Imaging Reporting and Data System and Modified Artificial Intelligence Thyroid Imaging Reporting and Data System for Thyroid Nodules: A Multicenter Retrospective Study. Thyroid. Published 7 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →