Minimum Continuous Glucose Monitor Data Required to Assess Glycemic Control in Youth with Type 1 Diabetes
Authors' conclusion
Although 14 days of CGM data are considered the gold standard, assessing ∼9.6 days of data in youth with T1D provides a reliable assessment of glycemia. For youth with higher TIR (≥70%) and lower CV (<36%), 7-day CGM data may prove sufficient.
Study context
- Population
- Youth <21 years with T1D and ≥70% continuous glucose monitor (CGM) active time in each window; real-world Dexcom G6 CGM data; 45.0% female, 76.9% non-Hispanic White, median age 14.6 years
- Participants
- 1,316 participants
- Exposure
- CGM time windows vs 14-day CGM data
- Outcome
- Agreement of GMI and TIR between 14-day and other CGM windows
Methodological detailsreal-world data
- Real-world data
Main finding
As reported in the abstract
Pearson correlation coefficients and interclass correlation coefficients (ICCs) between 14-day and GMI and TIR for all 8 windows
>0.9
Categorical agreement (subjects within acceptable thresholds for GMI and TIR) exceeded 90% only at
10 days
Observational data: associations, not effects.
Further findings
14-day CGM metrics
- Median 14-day CGM active time
- 97.2%
- GMI
- 7.4% (7.0, 7.9)
- TIR
- 60.5% (48.6, 70.6)
Agreement by subgroup (age, TIR, coefficient of variation (CV))
- No difference in agreement for CGM metrics according to categorical groupings of age
- Agreement stronger for youth with TIR ≥70% and CV <36%
Original publication
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