Reproductive endocrinology

Mid-pregnancy serum chemerin levels predict persistence of postpartum hypertension in patients with polycystic ovary syndrome

Eur J EndocrinolPublished Longitudinal cohort study

Main findingResult — go to the resultAdjusted odds ratio 6.66 95% CI 2.21–20.07

Authors' conclusion

Mid-pregnancy chemerin levels independently predict persistent hypertension after delivery in patients with PCOS and prior PHD.

Study context

Population
Women with and without polycystic ovary syndrome (PCOS) and previous pregnancy-related hypertensive disorders (PHD), studied 12 months after delivery; serum chemerin measured at 20 weeks of gestation
Participants
92 women
Exposure
Persistent hypertension vs normotensive at 12 months postpartum
Outcome
Persistent hypertension one year after delivery, predicted by mid-pregnancy serum chemerin
Follow-up
12 months after delivery

Main finding

As reported in the abstract

Adjusted odds ratio

6.66

95% CI 2.21–20.07

P = 0.0007

By group

Chemerin per 10 ng/mL
aOR 6.66 (95% CI 2.21–20.07); P = 0.0007

Per 10 ng/mL, as printed

Observational data: associations, not effects.

Further findings

Predictive performance of chemerin threshold (∼32.3 ng/mL) in women with PCOS

PPV
57.1%
NPV
82.9%

Original publication

Mid-pregnancy serum chemerin levels predict persistence of postpartum hypertension in patients with polycystic ovary syndrome. Eur J Endocrinol. Published 16 June 2026. doi:10.1093/ejendo/lvag102

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