Microvascular Complications Are Associated With Coronary Collateralization in Type 2 Diabetes and Chronic Occlusion
Authors' conclusion
Among T2DM patients with coronary CTO, the presence of DMC was associated with a high CC development.
Study context
- Population
- Consecutive T2D patients without previous cardiovascular history undergoing clinically indicated coronary angiography for chronic coronary syndrome with at least one coronary chronic total occlusion (CTO)
- Participants
- 157 patients
- Exposure
- T2D patients with vs without diabetic microvascular complications
- Diabetic microvascular complications (DMC)n = 75
- Outcome
- Presence and grading of angiographically visible coronary collateral (CC) development (Rentrop classification)
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Prevalence of CC
P = 0.006
Observational data: associations, not effects.
Further findings
Prevalence of high-grade CC
P = 0.001
Number of DMC per patient and high-grade coronary collateral (CC)
- Positive association between the number of DMC in each patient and the prevalence of high-grade CC
Original publication
Microvascular Complications Are Associated With Coronary Collateralization in Type 2 Diabetes and Chronic Occlusion. J Clin Endocrinol Metab. Published 7 July 2023. doi:10. 1210/ clinem/ dgad396
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