Metabolic Health Differences Among Women of Age-Based Pre-, Peri-, and Post-Menopausal Stages
Authors' conclusion
These results underscore the need for targeted menopausal stage-specific interventions to improve metabolic health and promote healthier lifestyle behaviors across the menopausal transition. Premenopausal women may benefit from early lifestyle and metabolic risk management, while peri- and postmenopausal women should prioritize maintaining physical activity and glycemic control.
Study context
- Population
- Women with or at risk of metabolic syndrome; age groups used as a proxy for menopausal stages
- Participants
- 718 women
- Exposure
- Age-based menopausal stages: Premenopausal (PreM) vs PeriM vs postmenopausal (PostM)
- PreMn = 108reference
- PeriMn = 218
- PostMn = 392
- Outcome
- Lifestyle behaviors and metabolic characteristics by group
Methodological detailsChi square, ANOVA and Kruskal-Wallis tests, Self-reported surveys for diet, stress, substance use; accelerometer-assessed daily steps; standardized anthropometric and bioclinical measurements
- Chi square, ANOVA and Kruskal-Wallis tests
- Self-reported surveys for diet, stress, substance use; accelerometer-assessed daily steps; standardized anthropometric and bioclinical measurements
Main finding
As reported in the abstract
- More negative health behaviors (diet, stress, substance use) and metabolic characteristics (BMI, waist circumference, HDL) in PreM (P < 0.05)
- PeriM vs PreM: lower BMI and higher HDL (both P < 0.05)
- PostM vs other 2 groups: lowest stress, physical activity and BMI; highest systolic BP, HbA1c and HDL (P < 0.05)
Observational data: associations, not effects.
Original publication
Metabolic Health Differences Among Women of Age-Based Pre-, Peri-, and Post-Menopausal Stages. Endocr Pract. Published 7 January 2026. doi:10.
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