Mapping of sex hormones in the testicular vein of healthy men
Authors' conclusion
Our results provide insight into the endocrine function of the testis under physiological conditions and constitute a reference for further research in male reproductive function.
Study context
- Population
- Healthy male volunteers aged 22–49 years without self-reported diseases and with normal semen quality
- Participants
- 7 healthy volunteers
- Comparison
- Testicular vein vs femoral artery
- Outcome
- Concentrations of steroid hormones, FSH, LH, inhibin B, AMH and INSL3 in testicular vein, femoral artery, femoral vein and seminal fluid
Methodological detailsangiographic catheterization under fluoroscopy, liquid chromatography mass spectrometry and immunoassays
- Angiographic catheterization under fluoroscopy
- Liquid chromatography mass spectrometry and immunoassays
Main finding
As reported in the abstract
Hormone concentrations, testicular vein vs femoral artery
- Testosterone higher in testicular vein vs femoral artery
- 66-fold
- 11-deoxycortisol higher in testicular vein vs femoral artery
- 4-fold
- 11-deoxycorticosterone higher in testicular vein vs femoral artery
- 20-fold
- INSL3 higher in testicular vein vs femoral artery
- 200-fold
- Inhibin B higher in testicular vein vs femoral artery
- 2-fold
Original publication
Mapping of sex hormones in the testicular vein of healthy men. J Clin Endocrinol Metab. Published 1 April 2026. doi:10.
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