Male Gender Expressivity and Diagnosis and Treatment of Cardiovascular Disease Risks in Men
Authors' conclusion
In this cohort study of US males, higher adolescent and younger adult MGE was associated with lower adult hypertension and diabetes diagnoses and treatment. These findings suggest that males with high MGE may bear distinctive risks and correspondingly benefit from tailored public health efforts to prevent downstream CVD.
Study context
- Population
- Male adolescents (age 12–18 years) in US Add Health, followed through younger adulthood (24–32 years) and adulthood (32–42 years); 64% non-Hispanic White, 80% privately insured
- Participants
- 4,230 eligible males
- Exposure
- Higher vs lower male gender expressivity (MGE) in adolescence and younger adulthood
- Outcome
- Self-reported diagnoses of CVD risk conditions (hypertension, diabetes, hyperlipidemia) and self-reported treatment with antihypertensive, hypoglycemic or lipid-lowering medications
- Follow-up
- Adulthood (age 32-42 years)
Methodological detailslongitudinal, multivariable regression adjusted for sociodemographic covariates, Data from Add Health waves I (1994-1995), IV (2008-2009), V (2016-2018); analyzed January 5, 2023, to August 28, 2024
- Longitudinal
- Multivariable regression adjusted for sociodemographic covariates
- Data from Add Health waves I (1994-1995), IV (2008-2009), V (2016-2018); analyzed January 5, 2023, to August 28, 2024
Main finding
As reported in the abstract
adulthood
- Higher younger adult MGE
- hypertension diagnosis 22% vs 26%; P < 0.001
- Higher younger adult MGE
- diabetes diagnosis 5% vs 8%; P < 0.001
- Higher younger adult MGE
- hyperlipidemia diagnosis 19% vs 24%; P < 0.001
- Higher younger adult MGE
- diabetes treatment 3% vs 5%; P = 0.02
- Per SD adolescent MGE: adult hypertension treatment
- −0.11 (95% CI, −0.16 to −0.6)
- Per SD adolescent MGE: adult diabetes diagnoses
- −0.15 (95% CI, −0.27 to −0.03)
- Younger adult MGE: adult hypertension diagnoses
- −0.04 (95% CI, −0.07 to −0.01)
- Younger adult MGE: adult hypertension treatment
- −0.07 (95% CI, −0.13 to −0.01)
- Younger adult MGE: adult diabetes treatment
- −0.10 (95% CI, −0.20 to −0.01)
Observational data: associations, not effects.
Original publication
Male Gender Expressivity and Diagnosis and Treatment of Cardiovascular Disease Risks in Men. JAMA Netw Open. Published 1 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →