Osteoporosis, bone & mineral

Machine learning is changing osteoporosis detection: an integrative review

Osteoporos IntPublished Integrative review

Authors' conclusion

These issues highlighted the importance of model interpretability in future machine learning research.

Study context

Population
Research of the past decade on machine learning for osteoporosis detection and screening
Comparison
Basic machine learning algorithms with clinical data vs deep learning with imaging data (X-ray, CT, MRI) for osteoporosis detection
Outcome
Performance of machine learning approaches for osteoporosis detection

Main finding

As reported in the abstract

  • Basic machine learning algorithms performed well with single structured data but had limitations with high-dimensional and unstructured imaging data
  • Deep learning can significantly improve detection accuracy by automatically extracting image features, especially in image histological analysis
  • Deep learning challenges: the "black-box" problem, heavy reliance on large amounts of labeled data, and difficulties in clinical interpretability

Original publication

Machine learning is changing osteoporosis detection: an integrative review. Osteoporos Int. Published 10 June 2025. doi:10.1007/s00198-025-07541-x

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