Lung Function Impairment and Risks of Incident Cardiovascular Diseases and Mortality Among People With Type 2 Diabetes: A Prospective Cohort Study
Authors' conclusion
Lung function impairment was associated with increased risks of CVD and all-cause mortality among individuals with T2D.
Study context
- Population
- Participants with T2D and free of cardiovascular disease (CVD), UK Biobank
- Participants
- 16,242 participants
- Exposure
- Lung function impairment vs preserved lung function
- Outcome
- Incident CVD and all-cause mortality
- Follow-up
- Median 13.9 years
Methodological detailsUK Biobank
- UK Biobank
Main finding
As reported in the abstract
Incident CVD
Estimate (95% CI)
OPvs Preserved lung function
adjusted subdistribution HR 1.19(1.05–1.35)
RPvs Preserved lung function
adjusted subdistribution HR 1.47(1.33–1.65)
OPvs Controlvs control group (PRISm classification)
subdistribution HR 1.20(1.06–1.36)
PRISmvs Controlvs control group
subdistribution HR 1.43(1.29–1.59)
- Events during follow-up: incident CVD cases
- 2,825
Observational data: associations, not effects.
Further findings
All-cause mortality
- Deaths documented
- 2,811
CVD prediction
- Adding lung function measurements significantly enhanced CVD prediction beyond the SCORE2-Diabetes model
Original publication
Lung Function Impairment and Risks of Incident Cardiovascular Diseases and Mortality Among People With Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care. Published 11 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →