Lower mitochondrial respiration does not lead to decreased fat oxidation in young African American women without obesity
Authors' conclusion
The data suggest that fat oxidation is not lower in AAW compared with White women, but additional studies are needed across exercise intensity, body weight, and age to confirm these results.
Study context
- Population
- Women aged 18.7–38.3 years with BMI < 28 kg/m²matched for age and BMI
- Participants
- 22 vs 22
- Exposure
- African American women vs White women
- African American women (AAW)n = 22
- White womenn = 22reference
- Outcome
- Fat oxidation (total, plasma and intramyocellular TG) during submaximal (50% VO2max) exercise
Methodological detailsmatched for age and BMI
- Matched for age and BMI
Main finding
As reported in the abstract
Respiratory quotient during exercise test
AAW
0.813
± 0.008
White women
0.810
± 0.008
P = 0.83
Observational data: associations, not effects.
Further findings
Absolute total and plasma fat oxidation
- Lower in AAW; adjusting for lower workload in AAW eliminated racial differences
Plasma and intramyocellular TG source of fat for oxidation
- No racial difference
Ex vivo fat oxidation
- No racial differences
Exercise efficiency
- Lower in AAW when adjusted to leg fat free mass
Original publication
Lower mitochondrial respiration does not lead to decreased fat oxidation in young African American women without obesity. Obesity (Silver Spring). Published 26 April 2023. doi:10.
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