Low Insulin-Like Growth Factor-1 Levels Are Associated With Myocardial Mechano-Energetic Efficiency in Older Individuals
Authors' conclusion
These findings suggest that low circulating IGF-1 levels are associated with depressed myocardial MEEi in older individuals. This highlights the potential importance of monitoring IGF-1 in clinical evaluations to assess cardiovascular health.
Study context
- Population
- Individuals older than 65 years with a broad spectrum of glucose tolerance, CATAMERI study
- Participants
- 490 participants
- Exposure
- IGF-1 tertiles
- Outcome
- Myocardial mechano-energetic efficiency (MEE) per gram of left ventricular mass (MEEi) by echocardiography, in relation to plasma IGF-1
Main finding
As reported in the abstract
Association of IGF-1 with myocardial MEEi
Correlation of IGF-1 with MEEi (positive)
r = 0.200
P < .001
Observational data: associations, not effects.
Original publication
Low Insulin-Like Growth Factor-1 Levels Are Associated With Myocardial Mechano-Energetic Efficiency in Older Individuals. J Clin Endocrinol Metab. Published 7 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →