Type 1 diabetes

Long-Term Prediction of Blood Glucose Levels in Type 1 Diabetes Using a CNN-LSTM-Based Deep Neural Network

J Diabetes Sci TechnolPublished Model development and validation study

Authors' conclusion

Our investigation demonstrated that our method achieved superior glucose forecasting compared with existing approaches in the literature, and thanks to its generalizability showed potential for real-life applications.

Study context

Population
People with T1D; Blood glucose (BG) prediction from historical glucose measurements, meal information and insulin intakes
Comparison
Replace-BG vs DIAdvisor
Outcome
BG prediction accuracy, 90-minute prediction horizon
Follow-up
90-minute PH
Methodological detailsdeep learning, CNN-LSTM
  • Deep learning
  • CNN-LSTM

Performance

As reported in the abstract

Test or modelMean absolute errorRoot mean square errorCoefficient of determinationCG-EGA accurate predictionsCG-EGA benign errorsCG-EGA erroneous predictions
Replace-BG17.30 ± 2.07 mg/dL23.45 ± 3.18 mg/dL84.13 ± 4.22%94.71 ± 3.89%1.81 ± 1.06%3.47 ± 1.12%
DIAdvisor18.23 ± 2.97 mg/dL25.12 ± 4.65 mg/dL82.34 ± 4.54%91.71 ± 4.32%2.51 ± 0.86%5.78 ± 1.72%

Mean absolute error

Replace-BG17.30 ± 2.07 mg/dL
DIAdvisor18.23 ± 2.97 mg/dL

Root mean square error

Replace-BG23.45 ± 3.18 mg/dL
DIAdvisor25.12 ± 4.65 mg/dL

Coefficient of determination

Replace-BG84.13 ± 4.22%
DIAdvisor82.34 ± 4.54%

CG-EGA accurate predictions

Replace-BG94.71 ± 3.89%
DIAdvisor91.71 ± 4.32%

CG-EGA benign errors

Replace-BG1.81 ± 1.06%
DIAdvisor2.51 ± 0.86%

CG-EGA erroneous predictions

Replace-BG3.47 ± 1.12%
DIAdvisor5.78 ± 1.72%

Original publication

Long-Term Prediction of Blood Glucose Levels in Type 1 Diabetes Using a CNN-LSTM-Based Deep Neural Network. J Diabetes Sci Technol. Published 25 April 2022. doi:10.1177/19322968221092785

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