Diabetes technology

Leveraging Continuous Glucose Monitoring Data as an Additional Source for Glucagon Prescription Behavior

Endocr PractPublished Retrospective chart review with quality improvement component

Authors' conclusion

Glucagon prescription remains suboptimal among patients with hypoglycemia on CGM reports. Provider engagement via QI can increase glucagon prescription.

Study context

Population
Adults with T1D, or T2D on insulin, SU or meglitinide, in a tertiary care health system; chart review March–October 2023
Participants
1,543 adults
Exposure
Hypoglycemia vs No hypoglycemia
  • Hypoglycemian = 170
Outcome
Percentage of glucagon prescription in patients with hypoglycemia on CGM reports
Methodological detailssingle tertiary care health system
  • Single tertiary care health system

Main finding

As reported in the abstract

Glucagon prescription in patients with time below range ≥4%
GroupValueIncident glucagon prescription
Hypoglycemia37%14%

Hypoglycemia

Value37%
Incident glucagon prescription14%
  • Hypoglycemia vs No hypoglycemia: P < 0.001 — 37% pre-existing prescription

Observational data: associations, not effects.

Further findings

OutcomeNo hypoglycemiaP value
Pre-existing or incident glucagon prescription by hypoglycemia severityBetween Mild and Severe28%P < 0.001
Pre-existing or incident glucagon prescription by hypoglycemia severityBetween Moderate and No hypoglycemiaP < 0.001
Pre-existing or incident glucagon prescription by hypoglycemia severityBetween Severe and No hypoglycemiaP < 0.001
  • Pre-existing or incident glucagon prescription by hypoglycemia severity: Mild 38%
  • Pre-existing or incident glucagon prescription by hypoglycemia severity: Moderate 49%
  • Pre-existing or incident glucagon prescription by hypoglycemia severity: Severe 63%

Glucagon prescribed after provider education (quality improvement (QI)) · 4 weeks

Patients whose providers received education who were prescribed glucagon
27 (39%) of 70
Top choices: glucagon emergency kit, glucagon autoinjector, inhaled glucagon

Original publication

Leveraging Continuous Glucose Monitoring Data as an Additional Source for Glucagon Prescription Behavior. Endocr Pract. Published 28 October 2024. doi:10.1016/j.eprac.2024.10.012

Composed by AI from the published abstract and checked against it. How Briefs are made →

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