Iodineminho Study: Iodine Supplementation and Prevalence of Iodine Deficiency In Pregnant Women
Authors' conclusion
In the Minho region of Portugal, fertile women have insufficient iodine intake. Additional public health measures are needed since the current recommendations for iodine supplementation for pregnancy are unsatisfactory to achieve adequate iodine status.
Study context
- Population
- Women recruited during preconception or in the first trimester of pregnancy, Minho region of Portugal
- Exposure
- Iodine supplement vs no supplement
- Outcome
- Prevalence of iodine deficiency (median UIC) and maternal thyroid status
Methodological detailsobservational
- Observational
Main finding
As reported in the abstract
Median urinary iodine concentration (UIC)
P = 0.002
- Pregnant women with adequate iodine status
- 15%
- Pregnant women with urinary iodine concentration (UIC) <50 µg/L
- 17%
Observational data: associations, not effects.
Further findings
UIC by timing of supplementation start · no influence of timing
P = 0.569
Thyroid function, first trimester
- Total thyroxine lower and FT3 higher in nonsupplemented women
- Tg lower with supplementation started in preconception vs nonsupplemented and vs started during gestation
Original publication
Iodineminho Study: Iodine Supplementation and Prevalence of Iodine Deficiency In Pregnant Women. J Clin Endocrinol Metab. Published 24 January 2024. doi:10.
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