Thyroid disease

Iodine status in Danish pregnant women after an increase in iodine fortification

Clin Endocrinol (Oxf)Published Cross-sectional study

Authors' conclusion

Despite an increase in iodine fortification and frequent use of iodine-containing supplements, iodine status in pregnant women in the North Denmark Region was insufficient. Results call for continued monitoring and attention to ensure adequate iodine status during pregnancy in Denmark.

Study context

Population
Pregnant women in the North Denmark Region referred for routine obstetric US in 2021; 88% used iodine-containing supplements
Participants
147 women
Exposure
Iodine status in 2021 vs 2012
  • 2021n = 147
Outcome
Median urinary iodine concentration (UIC), assessed against recommended range in pregnancy (150-249 µg/L)

Main finding

As reported in the abstract

Median UIC

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeP value
Sources of iodine intake in pregnancy2021 vs 2012 · lower daily dairy intake in 2021P = 0.008
Sources of iodine intake in pregnancy2021 vs 2012 · lower daily bread intake in 2021P < 0.001
Sources of iodine intake in pregnancy2021 vs 2012 · lower iodine content of supplement used in 2021P < 0.001

Original publication

Iodine status in Danish pregnant women after an increase in iodine fortification. Clin Endocrinol (Oxf). Published 10 July 2022. doi:10.1111/cen.14797

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