Thyroid disease

Intrathyroidal Ectopic Thymus: The Trick of the Trade

Horm Res PaediatrPublished Retrospective case series

Authors' conclusion

IET should be considered in the differential diagnosis of pediatric thyroid nodules especially in the first years of life.

Study context

Population
Children <18 years with thyroid nodules classified EU-TIRADS ≥3, tertiary pediatric endocrinology service, 2015–202510 presumed intrathyroidal ectopic thymus (IET)
Participants
21 children
Outcome
Occurrence and characteristics of IET
Methodological detailssingle-centre, tertiary pediatric endocrinology centre
  • Single-centre
  • Tertiary pediatric endocrinology centre

Main finding

As reported in the abstract

Children with EU-TIRADS ≥3 nodules presumed to have IET
10
Median age of children with EU-TIRADS ≥3 nodules (years)
10.6 (0.55-15)
Mean age of IET patients (years)
6.19 ± 3.93
Males among IET patients
50%
Normal thyroid function
9 patients
Subclinical hypothyroidism, resolved during follow-up
1 patient
Surgery or fine-needle aspiration biopsy (FNAB) in IET patients
0

Observational data: associations, not effects.

Original publication

Intrathyroidal Ectopic Thymus: The Trick of the Trade. Horm Res Paediatr. Published 5 September 2026. doi:10.1159/hrp/adaag019

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