International Consensus Guideline on the Diagnosis and Management of Endocrine Complications of β and α Thalassemia in Children and Adolescents
Methodological details14 experts from 13 countries representing 8 societies, literature reviewed up to 2024, ≥70% vote for agreement
- 14 experts from 13 countries representing 8 societies
- Literature reviewed up to 2024
- ≥70% vote for agreement
Recommendations
As issued by the authors
Adherence to modern transfusion and iron chelation can prevent or reverse endocrine complications
Regular screening before age 10 years in transfusion-dependent (TD) thalassemia and from 11 years onward in non-TD thalassemia
Patients after hematopoietic stem cell transplantation for βT major are at risk of endocrinopathies and should be managed as TD thalassemia
Original publication
International Consensus Guideline on the Diagnosis and Management of Endocrine Complications of β and α Thalassemia in Children and Adolescents. Horm Res Paediatr. Published 24 June 2025. doi:10.
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