Inpatient outcomes of diabetic ketoacidosis complicating pancreatic cancer: a national inpatient sample analysis
Main finding · In-hospital mortalityResult — go to the resultAdjusted odds ratio 1.76 95% CI 1.30–2.38Authors' conclusion
DKA complicates approximately 1% of US pancreatic cancer hospitalizations and independently predicts doubled mortality and markedly greater critical care utilization.
Study context
- Population
- Adult pancreatic cancer hospitalizations (ICD-10-CM C25), US National Inpatient Sample 2021–2023
- Participants
- 218,815 hospitalizations
- Exposure
- Pancreatic cancer hospitalizations with concurrent diabetic ketoacidosis (DKA) vs without DKA
- DKAn = 2,075
- Outcome
- In-hospital mortality
Methodological detailsNational Inpatient Sample 2021-2023, multivariable logistic regression
- National Inpatient Sample 2021-2023
- Multivariable logistic regression
Main finding
As reported in the abstract
Adjusted odds ratio
1.76
95% CI 1.30–2.38
DKAvs No DKA
aOR 1.76 (95% CI 1.30–2.38)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aOR (95% CI) | |
|---|---|---|
| AKI | 3.09 (2.49–3.83) | |
| Mechanical ventilation | 2.78 (1.92–4.03) | |
| ICU | 2.49 (1.90–3.27) | |
| Septic shock | 2.53 (1.86–3.43) | |
| Cardiac arrest | 2.40 (1.33–4.34) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Black race
DKA prevalence among pancreatic cancer hospitalizations
- Concurrent DKA
- 0.95% (n ≈ 2075)
Original publication
Inpatient outcomes of diabetic ketoacidosis complicating pancreatic cancer: a national inpatient sample analysis. Diabetes Metab. Published 4 August 2026. doi:10. 1016/ j. diabet. 2026. 101786
Composed by AI from the published abstract and checked against it. How Briefs are made →