Endocrine oncology

Influence of Radioiodine Therapy on Oral Health and Salivary Production in Patients With Differentiated Thyroid Carcinoma

Endocr PractPublished Cross-sectional study

Authors' conclusion

Good or very good oral health was observed in 60% of patients with DTC after RIT, 15% reported hyposalivation, and 13%, frequent xerostomia. Higher number and higher total activity of radioiodine administered, as well as reduction in the volume and heterogeneous texture of parotid gland on ultrasound were predictive factors of lower salivary flow.

Study context

Population
Patients with differentiated thyroid carcinoma (DTC) after ablative and/or adjuvant RAI
Participants
67 patients
Outcome
Oral health and salivary production after RAI

Main finding

As reported in the abstract

Oral health very good or good
60%
No dental plaque or a slight amount
84%
Normal-looking gums
53%
Reported hyposalivation
15%
Frequent xerostomia
13%

Observational data: associations, not effects.

Original publication

Influence of Radioiodine Therapy on Oral Health and Salivary Production in Patients With Differentiated Thyroid Carcinoma. Endocr Pract. Published 10 January 2025. doi:10.1016/j.eprac.2025.01.001

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