Gestational diabetes & diabetes in pregnancy
Influence of Gestational Diabetes Mellitus on Diabetes Risk and Glycemic Control in a Retrospective Population-Based Cohort
Main finding · DiabetesResult — go to the resultAdjusted hazard ratio 11.5 95% CI 10.8–12.3Authors' conclusion
Understanding racial/ethnic differences in the influence of GDM on diabetes progression is critical to disrupt life course cardiometabolic disparities.
Study context
- Population
- Postpartum women with New York City (NYC) births 2009–2011, linked with NYC A1C Registry 2009–2017; baseline diabetes excludedbirth cohort
- Participants
- 336,276 women
- Exposure
- Gestational diabetes mellitus (GDM) vs no GDM
- Outcome
- Time to diabetes onset (two A1C tests ≥6.5% from 12 weeks postpartum onward)
Methodological detailsCox regression with time-varying exposure, adjusted for sociodemographic and clinical factors, stratified by race/ethnicity
- Cox regression with time-varying exposure
- Adjusted for sociodemographic and clinical factors
- Stratified by race/ethnicity
Main finding
Diabetes
Adjusted hazard ratio
11.5
95% CI 10.8–12.3
By group
GDMvs No GDM
aHR 11.5 (95% CI 10.8–12.3)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Glycemic control (first A1C <7.0% after diagnosis)Lower likelihood with GDM | 0.85 (0.79–0.92) | |
| Glycemic control, Black women | 0.77 (0.68–0.88) | |
| Glycemic control, Hispanic women | 0.84 (0.74–0.95) | |
| 0.512Adjusted hazard ratio (log scale) |
Sensitivity analysis: adjustment for screening bias and loss to follow-up
- Modestly attenuated racial/ethnic differences in diabetes risk; little influence on glycemic control
Original publication
Influence of Gestational Diabetes Mellitus on Diabetes Risk and Glycemic Control in a Retrospective Population-Based Cohort. Diabetes Care. Published 21 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →