Obesity

Infant social withdrawal and rapid infant weight gain

Int J Obes (Lond)Published Cohort study

Main finding · RIWGResult — go to the resultAdjusted odds ratio 1.19 95% CI 1.03–1.37

Authors' conclusion

We found an association between infant social withdrawal and subsequent rapid infant weight gain independently of an array of known risk factors, which may expand our understanding of the developmental origins of excess weight gain and its association with early childhood mental health.

Study context

Population
Children born 2015–19 in Copenhagen; data from health visitors' records linked to register data
Participants
12,468 children
Exposure
Infant social withdrawal vs no signs of social withdrawal
Outcome
Rapid infant weight gain (RIWG)
Methodological detailsregister-linked, multivariate logistic regression
  • Register-linked
  • Multivariate logistic regression

Main finding

RIWG

Adjusted odds ratio

1.19

95% CI 1.03–1.37

P = 0.017

Social withdrawalvs No social withdrawal
aOR 1.19 (95% CI 1.03–1.37); P = 0.017

As reported in the abstract

Observational data: associations, not effects.

Further findings

Other factors associated with rapid infant weight gain (RIWG)

RIWG more likely among boys, firstborns, children born SGA, and those whose mothers smoked during pregnancy or had higher pre-pregnancy BMI
Higher birth weight and breastfeeding >4 months were protective
No associations with maternal postpartum depression, low education, parental labor market status or maternal age

Original publication

Infant social withdrawal and rapid infant weight gain. Int J Obes (Lond). Published 22 December 2025. doi:10.1038/s41366-025-01996-y

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