Individual participant data meta-analysis of eating behaviour traits as effect modifiers in acceptance and commitment therapy-based weight management interventions
Authors' conclusion
Findings suggest potential non-linear interaction effects of ACT with internal disinhibition but require replication in confirmatory trials. These results may help guide further research on precision approaches based on EBTs.
Study context
- Population
- Adults with BMI ≥ 25 kg/m² in trials of and Commitment Therapy (ACT)-based interventions
- Participants
- 2,535 adults15 trials
- Comparison
- ACT-based interventions vs control; baseline eating behaviour traits (EBTs) as effect modifiers
- Outcome
- Moderating effects of baseline EBTs on percentage weight change
Methodological detailspre-registered, one-stage, exploratory
- Pre-registered
- One-stage
- Exploratory
Pooled result
As reported in the abstract
Interaction of ACT vs control with baseline EBTs on % weight change
Added difference in weight change, medium vs high internal disinhibition, baseline to 12 months after intervention end
−4.47%
95% CI −1.15, −7.73
Further pooled results
Sensitivity analyses
- Greater intervention benefit with medium rather than high emotional eating (trials that reduced experiential avoidance; trials using three-factor eating questionnaire) and internal disinhibition (participants with ≥60% attendance)
Original publication
Individual participant data meta-analysis of eating behaviour traits as effect modifiers in acceptance and commitment therapy-based weight management interventions. Int J Obes (Lond). Published 10 April 2025. doi:10.
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