Increased impulsivity and higher odds of compulsive shopping among cabergoline-treated patients with prolactinoma: a case-control study
Authors' conclusion
Patients with prolactinoma treated with cabergoline exhibit increased impulsivity, particularly in the attentional domain, along with higher odds of compulsive shopping.
Study context
- Population
- Patients with prolactinoma receiving cabergoline and healthy controls
- Participants
- 131 vs 131
- Comparison
- Cabergoline-treated patients with prolactinoma vs healthy controls
- Cabergolinen = 131
- Healthy controlsn = 131reference
- Outcome
- Impulsivity (Barratt Impulsiveness Scale, BIS-11) and impulse control disorders (hypersexuality, gambling, compulsive shopping, punding)
Main finding
As reported in the abstract
Impulsivity (BIS-11)
- Higher overall impulsivity in cabergoline-treated patients: increased Barratt Impulsiveness Scale (BIS-11) scores and higher proportion with increased impulsivity (BIS-11 ≥ 60)
- Attentional impulsivity remained significantly higher in patients after multivariable adjustment
Observational data: associations, not effects.
Further findings
Impulse control disorders
- More than fourfold higher odds of compulsive shopping in patients vs controls
- No significant differences for other impulse control disorders (ICDs)
Educational level
- Lower educational level associated with higher impulsivity across all BIS-11 domains and with compulsive shopping
Original publication
Increased impulsivity and higher odds of compulsive shopping among cabergoline-treated patients with prolactinoma: a case-control study. Pituitary. Published 24 July 2026. doi:10. 1007/ s11102-026-01728-z
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