Incidence and Risk Factors of Diagnosed Young-Adult-Onset Type 2 Diabetes in the U.S.: The National Health Interview Survey 2016–2022
Authors' conclusion
This study quantified the incidence of diagnosed young-adult-onset T2D in U.S. adults and identified its distinct risk factor profile. Targeted prevention strategies for young-adult-onset T2D are needed for minority and socioeconomically disadvantaged people and those with cardiometabolic diseases.
Study context
- Population
- Adults aged 18–79 years with self-reported diabetes type, National Health Interview Survey 2016–2022, noninstitutionalized U.S. civilian population
- Participants
- 142,884 adults
- Exposure
- Young-adult onset vs Middle-age onset vs Older-adult onset
- Outcome
- Incidence of diagnosed young-adult-onset T2D and its risk factors
Methodological detailsnationally representative survey, multivariable logistic regression
- Nationally representative survey
- Multivariable logistic regression
Main finding
As reported in the abstract
Incidence of diagnosed young-adult-onset T2D
Young-adult onset
3.0 per 1,000 adults
95% CI 2.6–3.5
Observational data: associations, not effects.
Further findings
Risk factors for young-adult-onset T2D
| aOR (95% CI) | ||
|---|---|---|
| Lipid-lowering medication useStrongest risk factors | 13.15 (8.85–19.55) | |
| Antihypertensive medication useStrongest risk factors | 11.89 (7.97–17.73) | |
| 0.050.21520Adjusted odds ratio (log scale) |
| Outcome | aOR (95% CI) | |
|---|---|---|
| Risk factors for young-adult-onset T2DObesity (BMI ≥30 kg/m²)vs BMI <25 kg/m²Strongest risk factors | 10.89 (6.69–17.7) | |
| 0.050.21520Adjusted odds ratio (log scale) |
- Risk factors for young-adult-onset T2D — These risk factors, plus hypertension, hyperlipidemia and coronary heart disease, more strongly associated with young-adult-onset than later-onset T2D
- up to 4.5 times higher aORs
Original publication
Incidence and Risk Factors of Diagnosed Young-Adult-Onset Type 2 Diabetes in the U.S.: The National Health Interview Survey 2016–2022. Diabetes Care. Published 3 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →