Improvements in Sperm Motility Following Low- or High-Intensity Dietary Interventions in Men With Obesity
Authors' conclusion
LED or BDI may be sufficient to improve sperm motility in men with obesity. The effects of paternal dietary intervention on fertility outcomes requires investigation.
Study context
- Population
- Men with obesity (18–60 years) with normal sperm concentration (normal count) or oligozoospermia24 normal count, 43 oligozoospermia · or oligozoospermia 43
- Comparison
- 800 kcal/day low-energy diet for 16 weeks vs brief dietary intervention
- Primary endpoint
- Semen parameters
- Follow-up
- Baseline and 16 weeks
Methodological detailsrandomized 1:1, stratified by sperm concentration (normal count or oligozoospermia)
- Randomized 1:1
- Stratified by sperm concentration (normal count or oligozoospermia)
Primary result
As reported in the abstract
Postintervention total motility (TM) and progressive motility (PM), LED vs BDI · 16 weeks
- No differences in postintervention total motility (TM) or progressive motility (PM) between low-energy diet (LED) and brief dietary intervention (BDI) in men with normal count or oligozoospermia
Further findings
Weight loss, men with normal count · more weight loss with LED
P < 0.001
Weight loss, men with oligozoospermia · more weight loss with LED
P < 0.001
Change from baseline in TM and PM, men with normal count · baseline to 16 weeks
- TM increased after LED (P < .05)
- 48 ± 17% to 60 ± 10%
- TM increased after BDI (P < .0001)
- 52 ± 8% to 61 ± 6%
- PM increased after LED (P < .05)
- 41 ± 16% to 53 ± 10%
- PM increased after BDI (P < .001)
- 45 ± 8% to 54 ± 65%
Change from baseline in TM and PM, men with oligozoospermia · baseline to 16 weeks
- TM increased after LED (P < .05)
- 35% [26] to 52% [16]
- TM after BDI (P = .0587)
- 43% [28] to 50% [23]
- PM increased after LED (P < .05)
- 29% [23] to 46% [18]
- PM increased after BDI (P < .05)
- 33% [25] to 44% [25]
Original publication
Improvements in Sperm Motility Following Low- or High-Intensity Dietary Interventions in Men With Obesity. J Clin Endocrinol Metab. Published 1 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →