Impact of school‐supervised ultra‐long‐acting basal insulin injections on ketosis in youth with T1D and elevated haemoglobin A1c: A pilot study
Authors' conclusion
In youth with T1D at high risk for DKA, daily supervised long-acting insulin administration decreased the probability of elevated ketone levels on subsequent school days, regardless of basal insulin type. A larger sample size may have demonstrated that the longer action profile of degludec would offer additional protection from ketosis during days of not attending school.
Study context
- Population
- Youth aged 10–18 years with T1D managed with injections and haemoglobin A1c (HbA1c) ≥ 8.5%28 analysed
- Comparison
- School-supervised degludec vs glargine
Methodological detailspilot, During COVID closures, the research team supervised procedures remotely
- Pilot
- During COVID closures, the research team supervised procedures remotely
Primary result
As reported in the abstract
Elevated BHB (≥0.6 mmol/L) after 2 days of unsupervised basal insulin doses at home
P = 0.3
Further findings
- HbA1c unchanged in both groups
Original publication
Impact of school‐supervised ultra‐long‐acting basal insulin injections on ketosis in youth with T1D and elevated haemoglobin A1c: A pilot study. Diabet Med. Published 10 May 2023. doi:10.
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