Type 1 diabetes

Youth with type 1 diabetes mellitus are more inactive and sedentary than apparently healthy peers: A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis

Authors' conclusion

Keeping in mind the heterogeneity between studies in the design, population and assessment, our findings show that children and adolescents with type 1 diabetes seem to be less active, more sedentary, and have lower cardiorespiratory fitness levels than their healthy peers.

Study context

Population
Children and adolescents with T1D and healthy peers; 53% girls
Participants
4,751 children35 studies
Comparison
Youth with T1D vs healthy peers
  • T1Dn = 2,452
Outcome
Physical activity, sedentary behaviour and cardiorespiratory fitness
Methodological detailsrandom effects inverse-variance models, Hartung-Knapp-Sidik-Jonkman adjustment
  • Random effects inverse-variance models
  • Hartung-Knapp-Sidik-Jonkman adjustment

Pooled result

As reported in the abstract

T1D vs Healthy peersCohen's d (sedentary behaviour) (95% CI)
More sedentary with T1D; corresponds to 63.3 min/day of sedentary time (accelerometry)
0.33(0.06–0.61)
Less physically active with T1D; corresponds to −12.72 min/day of moderate-to-vigorous physical activity
Cohen's d (physical activity) −0.23 (95% CI - 0.42 to −0.04)
Corresponds to −4.07 ml/kg/min of maximum/peak oxygen consumption
Cohen's d (cardiorespiratory fitness) −0.52 (95% CI - 0.73 to −0.31)

Further pooled results

OutcomeOR (95% CI)
Meeting international physical activity recommendationsLess likely with T1D0.44 (0.31–0.62)

Original publication

Youth with type 1 diabetes mellitus are more inactive and sedentary than apparently healthy peers: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 9 May 2023. doi:10.1016/j.diabres.2023.110697

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