Gestational diabetes & diabetes in pregnancy

Impact of Real Time, Flash and Retrospective Continuous Glucose Monitoring on Feto‐Maternal Outcomes in Women With Gestational Diabetes and Pre‐Gestational Diabetes: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis of Randomized Controlled Trials

Diabetes Obes MetabPublished Systematic review and meta-analysis of randomised trials

Authors' conclusion

RT-CGM probably reduces NICU admission (moderate-certainty), but TSA indicates that current evidence is still information-size limited

Study context

Population
Pregnant women with gestational diabetes mellitus (GDM) or pregestational diabetesRandomized controlled trials (RCTs) (13 GDM, 4 pregestational)
Participants
17 women
Comparison
Continuous glucose monitoring (CGM) vs self-monitoring of blood glucose (SMBG)
Outcome
NICU admission and large-for-gestational-age (LGA) infants
Methodological detailstrial sequential analysis, CGM modalities and diabetes subtypes analysed separately
  • Trial sequential analysis
  • CGM modalities and diabetes subtypes analysed separately

Pooled result

As reported in the abstract

Each group vs SMBGOdds ratio (95% CI)P value
Real-time CGMNICU admission, GDM; I 2 = 0%
0.55(0.34–0.90)
P = 0.02
Retrospective CGMLGA, GDM; I 2 = 0%
0.46(0.22–0.98)
P = 0.048

Further pooled results

Other feto-maternal outcomes (birthweight, macrosomia, Caesarean delivery, hypertensive disorders, neonatal hypoglycaemia, preterm birth)

No significant difference between CGM and SMBG

Feto-maternal outcomes in pregestational diabetes

No CGM modality conferred measurable benefit

Original publication

Impact of Real Time, Flash and Retrospective Continuous Glucose Monitoring on Feto‐Maternal Outcomes in Women With Gestational Diabetes and Pre‐Gestational Diabetes: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis of Randomized Controlled Trials. Diabetes Obes Metab. Published 7 April 2026. doi:10.1111/dom.70743

Composed by AI from the published abstract and checked against it. How Briefs are made →

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