Impact of Syringe and Needle Reuse on the Clinical Outcomes of Patients With Type 2 Diabetes: A 12-Week Randomized Clinical Trial
Authors' conclusion
The reuse of syringes and needles is associated with a modest increase in lipohypertrophy/nodules but does not have a short-term impact on glycemic control in patients with type 2 diabetes.
Study context
- Population
- Adults with T2D who had reused syringes and needles at least three times; mean ± SD age 59.7 ± 8.8 years, 59% women, median diabetes duration 18 years (IQR 10–25), mean BMI 31.7 ± 6.7 kg/m²
- Participants
- 71 adults
- Comparison
- No reuse vs reuse of insulin syringes and needles
- Primary endpoint
- Glycemic control, pain scores and skin complications (ecchymosis, lipohypertrophy, nodules, infection)
- Follow-up
- Baseline and 4, 8, and 12 weeks
Primary result
As reported in the abstract
Primary outcomes: lipohypertrophy/nodules, pain, glycemic control, total skin complications
Increase in lipohypertrophy/nodules with reuse
0.16 ± 0.08
P = 0.040
Secondary outcomes
Quality of life and microbiological contamination
- No difference in quality of life or microbiological contamination
Treatment adherence
- Both groups improved treatment adherence, with a greater increase in the reuse group
Safety
- Increase in lipohypertrophy/nodules with reuse
- 0.16 ± 0.08, P = 0.040
- No difference in total number of skin complications
Original publication
Impact of Syringe and Needle Reuse on the Clinical Outcomes of Patients With Type 2 Diabetes: A 12-Week Randomized Clinical Trial. Diabetes Care. Published 15 October 2024. doi:10.
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