Impact of Subtype Variability on Clinical Features in Papillary Thyroid Cancer
An erratum to this article was published (J Clin Endocrinol Metab, 16 Oct 2026 ↗)
Authors' conclusion
We concluded that patients with mixed subtypes had clinical features that were more severe than those with a single subtype, suggesting that postoperative management warrants caution.
Study context
- Population
- Patients with thyroid cancer who underwent surgery for papillary thyroid cancer (PTC), March 2009–December 2021, Korea
- Participants
- 26,449 patients
- Exposure
- Mixed PTC subtypes vs single subtypes
- Outcome
- Clinical features by PTC subtype
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Significant differences among the groups based on PTC subtypes
- Conventional with aggressive showed more aggressive clinical features than conventional alone
- Conventional with nonaggressive showed aggressive features vs nonaggressive alone
Observational data: associations, not effects.
Original publication
Impact of Subtype Variability on Clinical Features in Papillary Thyroid Cancer. J Clin Endocrinol Metab. Published 19 November 2025. doi:10. 1210/ clinem/ dgaf531
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