Endocrine oncology

Impact of Subtype Variability on Clinical Features in Papillary Thyroid Cancer

J Clin Endocrinol MetabPublished Cross-sectional study

An erratum to this article was published (J Clin Endocrinol Metab, 16 Oct 2026 ↗)

Authors' conclusion

We concluded that patients with mixed subtypes had clinical features that were more severe than those with a single subtype, suggesting that postoperative management warrants caution.

Study context

Population
Patients with thyroid cancer who underwent surgery for papillary thyroid cancer (PTC), March 2009–December 2021, Korea
Participants
26,449 patients
Exposure
Mixed PTC subtypes vs single subtypes
Outcome
Clinical features by PTC subtype
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

  • Significant differences among the groups based on PTC subtypes
  • Conventional with aggressive showed more aggressive clinical features than conventional alone
  • Conventional with nonaggressive showed aggressive features vs nonaggressive alone

Observational data: associations, not effects.

Original publication

Impact of Subtype Variability on Clinical Features in Papillary Thyroid Cancer. J Clin Endocrinol Metab. Published 19 November 2025. doi:10.1210/clinem/dgaf531

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.