Impact of live microbe intake on cardiovascular disease and mortality in adults with diabetes: A nationwide cohort study
Main finding · CVDResult — go to the resultOdds ratio 0.55 95 % CI 0.33–0.92Authors' conclusion
Moderate consumption of dietary live microbes is associated with reduced CVD risk and cardiovascular mortality in adults with diabetes. These findings suggest potential cardiovascular benefits from including LM in the diet of diabetic patients.
Study context
- Population
- Adults with diabetes, National Health and Nutrition Examination Survey (NHANES) 2001–2010, mortality follow-up through December 31, 2019
- Participants
- 3,955 adults
- Exposure
- Low, medium or high dietary live microbe intake vs non-consumers
- Outcome
- CVD and cardiovascular mortality
Methodological detailsnationwide, NHANES 2001–2010, weighted logistic regression, weighted Cox proportional hazards models
- Nationwide
- NHANES 2001–2010
- Weighted logistic regression
- Weighted Cox proportional hazards models
Main finding
CVD
Odds ratio
0.55
95 % CI 0.33–0.92
MLMvs Non-consumers
OR 0.55 (95 % CI 0.33–0.92)
As reported in the abstract
- Participants with cardiovascular disease (CVD)
- 1,064
Observational data: associations, not effects.
Further findings
| Outcome | HR (95 % CI) | |
|---|---|---|
| Cardiovascular mortality · median follow-up 10.5 yearsMLMvs Non-consumers | 0.65 (0.49–0.86) | |
| 0.512Hazard ratio (log scale) |
- Cardiovascular mortality — Cardiovascular deaths
- 432
Original publication
Impact of live microbe intake on cardiovascular disease and mortality in adults with diabetes: A nationwide cohort study. Diabetes Res Clin Pract. Published 29 November 2024. doi:10. 1016/ j. diabres. 2024. 111942
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