The impact of a fracture liaison service with in-hospital anti-osteoporosis treatment on subsequent hip fracture and mortality rates—a single-center retrospective study
Main finding · Subsequent HFResult — go to the resultHazard ratio 0.52 95% CI 0.37–0.74Authors' conclusion
The implementation of an in-hospital FLS facilitated prompt initiation of anti-osteoporosis treatment following a HF, increased follow-up and treatment rates, and resulted in a 48% reduction in subsequent HF risk and a 29% reduction in mortality rates.
Study context
- Population
- Patients aged 65 years and older admitted with an osteoporotic hip fracture (HF), transferred after surgery for rehabilitation in the geriatrics department
- Participants
- 448 vs 318
- Exposure
- Geriatric-FLS vs geriatric-pre-FLS cohorts
- Fracture liaison service (FLS)n = 448
- PRE-FLSn = 318reference
- Outcome
- Subsequent HF and mortality rate
Methodological detailssingle-center, multivariable Cox regression
- Single-center
- Multivariable Cox regression
Main finding
Subsequent HF
Hazard ratio
0.52
95% CI 0.37–0.74
P < 0.001
FLSvs PRE-FLS
HR 0.52 (95% CI 0.37–0.74); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Mortality29% decrease in mortality rate; multivariable Cox regression | 0.71 (0.54–0.92) | P = 0.011 | |
| 0.512Hazard ratio (log scale) |
Original publication
The impact of a fracture liaison service with in-hospital anti-osteoporosis treatment on subsequent hip fracture and mortality rates—a single-center retrospective study. Osteoporos Int. Published 18 December 2024. doi:10.
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