Identifying the Relationship Between Continuous Glucose Monitor Time in Range and Basal Insulin Adherence in People With Type 2 Diabetes
Authors' conclusion
Our study indicates a relationship between basal insulin adherence and TIR in people with insulin-treated T2D. This seems to underscore the role of basal insulin adherence for optimal glycemic outcomes and utilizing TIR as a clinical marker. Furthermore, the results suggest that the magnitude of deviation from the recommended basal insulin dose impacts glycemic control, indicating dose deviation ≤20% as a more accurate metric for quantifying adherence.
Study context
- Population
- Insulin-treated people aged ≥18 years with T2D, with continuous glucose monitors (CGM) and connected insulin pen data
- Participants
- 106 people
- Exposure
- Basal insulin adherence metrics vs time in range (TIR)
- Outcome
- Relationship (R2) between basal insulin adherence and CGM TIR
Methodological detailsunivariate linear regression
- Univariate linear regression
Main finding
As reported in the abstract
| Group | Value | P |
|---|---|---|
| Dose deviation ≤20% | R2 0.67 | P = .006 |
| Dose deviation | R2 0.43 | P = .08 |
| Traditional metric | R2 0.35 | P =.23 |
Value
Dose deviation ≤20%R2 0.67
Dose deviationR2 0.43
Traditional metricR2 0.35
P
Dose deviation ≤20%P = .006
Dose deviationP = .08
Traditional metricP =.23
Observational data: associations, not effects.
Original publication
Identifying the Relationship Between Continuous Glucose Monitor Time in Range and Basal Insulin Adherence in People With Type 2 Diabetes. J Diabetes Sci Technol. Published 10 November 2024. doi:10.
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