Lipids & metabolic liver disease
HOMA-IR and TyG index differ for their relationship with dietary, anthropometric, inflammatory factors and capacity to predict cardiovascular risk
Authors' conclusion
The TyG index represents a better predictor of cardiovascular risk compared to HOMA-IR which, instead, exhibits a stronger relationship with anthropometric, inflammatory and nutritional variables.
Study context
- Population
- Subjects aged 55–80 years with anthropometric, metabolic and nutritional characterisation
- Participants
- 438 subjects
- Exposure
- HOMA-IR vs TyG index
- Outcome
- Relationship with anthropometric, dietary, inflammatory factors and prediction of cardiovascular risk
Main finding
As reported in the abstract
- HOMA-IR and TyG index correlated positively with BMI, waist circumference, fat mass, systolic and diastolic blood pressure, interleukin-18 and C-reactive protein
- Only HOMA-IR correlated with dietary factors
- Adjusted for age and sex, waist circumference and interleukin-18 were stronger predictors of HOMA-IR than of the TyG index
- TyG index, but not HOMA-IR, predicted 10-year cardiovascular risk
Observational data: associations, not effects.
Original publication
HOMA-IR and TyG index differ for their relationship with dietary, anthropometric, inflammatory factors and capacity to predict cardiovascular risk. Diabetes Res Clin Pract. Published 17 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →