Type 1 diabetes

Higher population density protects from type 1 diabetes? Dissecting the literature through meta-analysis

Diabetes Res Clin PractPublished Meta-analysis

Authors' conclusion

Our results are not in line with the view that urbanization would systematically increase the risk of type 1 diabetes and highlight the variability of the association among geographic regions.

Study context

Population
Studies of population density and T1D risk, literature up to February 22, 2025; 14 countries18 studies, T1D cases
Participants
82,493 participants
Comparison
Higher vs lower population density
Outcome
Risk of T1D

Pooled result

As reported in the abstract

Association between population density and T1D risk

Inverse association between population density and T1D risk: RR (95% CI), P

0.86

0.81, 0.91P < 0.001

Original publication

Higher population density protects from type 1 diabetes? Dissecting the literature through meta-analysis. Diabetes Res Clin Pract. Published 22 May 2025. doi:10.1016/j.diabres.2025.112272

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