Type 2 & other diabetes

High prevalence of fatty pancreas disease in type 2 diabetes mellitus: a meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of observational studies

Authors' conclusion

Approximately half of patients with T2DM have concomitant FPD, indicating a substantial yet underrecognized metabolic burden.

Study context

Population
People with T2D; observational studies reporting fatty pancreas disease (FPD) prevalence, PubMed and Embase searched until October 27, 2025
Participants
6,369 people12 studies
Outcome
Pooled prevalence of fatty pancreas disease (FPD)
Methodological detailsgeneralized linear mixed model
  • Generalized linear mixed model

Pooled result

As reported in the abstract

Pooled prevalence of FPD in T2D

Pooled prevalence of FPD

54.28%

95% CI 37.70 to 69.96

Further pooled results

FPD prevalence by region (subgroup) · tended to be lower in Asian studies

P = 0.06

FPD prevalence by study size and setting (subgroup)

Higher in smaller studies (<100 individuals)
67.55%
Higher in clinic/hospital-based settings
57.90%

FPD prevalence by intrapancreatic fat deposition (IPFD) measurement method or median study year of enrollment (subgroup)

No significant differences

Original publication

High prevalence of fatty pancreas disease in type 2 diabetes mellitus: a meta-analysis. Diabetes Res Clin Pract. Published 10 March 2026. doi:10.1016/j.diabres.2026.113149

Composed by AI from the published abstract and checked against it. How Briefs are made →

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