High prevalence of fatty pancreas disease in type 2 diabetes mellitus: a meta-analysis
Authors' conclusion
Approximately half of patients with T2DM have concomitant FPD, indicating a substantial yet underrecognized metabolic burden.
Study context
- Population
- People with T2D; observational studies reporting fatty pancreas disease (FPD) prevalence, PubMed and Embase searched until October 27, 2025
- Participants
- 6,369 people12 studies
- Outcome
- Pooled prevalence of fatty pancreas disease (FPD)
Methodological detailsgeneralized linear mixed model
- Generalized linear mixed model
Pooled result
As reported in the abstract
Pooled prevalence of FPD in T2D
Pooled prevalence of FPD
54.28%
95% CI 37.70 to 69.96
Further pooled results
FPD prevalence by region (subgroup) · tended to be lower in Asian studies
P = 0.06
FPD prevalence by study size and setting (subgroup)
- Higher in smaller studies (<100 individuals)
- 67.55%
- Higher in clinic/hospital-based settings
- 57.90%
FPD prevalence by intrapancreatic fat deposition (IPFD) measurement method or median study year of enrollment (subgroup)
- No significant differences
Original publication
High prevalence of fatty pancreas disease in type 2 diabetes mellitus: a meta-analysis. Diabetes Res Clin Pract. Published 10 March 2026. doi:10. 1016/ j. diabres. 2026. 113149
Composed by AI from the published abstract and checked against it. How Briefs are made →