High incidence of eating disorders in individuals with type 2 diabetes and their association with cardiovascular and mortality risks
Main finding · Incidence of EDResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.12–1.28Authors' conclusion
Type 2 diabetes mellitus and ED increased all-cause mortality, composite CVD, CV-related mortality and CV-related hospitalisation. ED incidence was higher among insulin users with type 2 diabetes. Therefore, early diagnosis and personalised interventions are crucial to improve outcomes in this high-risk population.
Study context
- Population
- Adults aged ≥20 years who underwent health examinations between 2013 and 2014
- Participants
- 1,896,493 adults
- Exposure
- T2D vs general population
- Outcome
- Incidence of eating disorders (ED)
Methodological detailsnationwide, time-varying Cox analyses
- Nationwide
- Time-varying Cox analyses
Main finding
Incidence of ED
Adjusted hazard ratio
1.20
95% CI 1.12–1.28
T2Dvs General population
aHR 1.20 (95% CI 1.12–1.28)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Incidence of eating disorders (ED) by insulin use (vs general population)
- Insulin users, aHR
- 1.30 [1.09, 1.54] (95% CI)
- Non-insulin users, aHR
- 1.18 [1.11, 1.27] (95% CI)
- Incidence of ED higher among insulin users than non-insulin users
Outcomes in T2D with ED
- All-cause mortality, aHR
- 2.57 [2.30, 2.87] (95% CI)
- Composite CVD, aHR
- 1.68 [1.44, 1.96] (95% CI)
- Cardiovascular (CV)-related mortality, aHR
- 2.68 [1.94, 3.70] (95% CI)
- CV-related hospitalisation, aHR
- 1.61 [1.37, 1.89] (95% CI)
- Increased rates in the T2D with ED group
Original publication
High incidence of eating disorders in individuals with type 2 diabetes and their association with cardiovascular and mortality risks. Diabetologia. Published 26 November 2025. doi:10. 1007/ s00125-025-06615-z
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