Type 2 & other diabetes

High incidence of eating disorders in individuals with type 2 diabetes and their association with cardiovascular and mortality risks

DiabetologiaPublished Retrospective cohort study

Main finding · Incidence of EDResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.12–1.28

Authors' conclusion

Type 2 diabetes mellitus and ED increased all-cause mortality, composite CVD, CV-related mortality and CV-related hospitalisation. ED incidence was higher among insulin users with type 2 diabetes. Therefore, early diagnosis and personalised interventions are crucial to improve outcomes in this high-risk population.

Study context

Population
Adults aged ≥20 years who underwent health examinations between 2013 and 2014
Participants
1,896,493 adults
Exposure
T2D vs general population
Outcome
Incidence of eating disorders (ED)
Methodological detailsnationwide, time-varying Cox analyses
  • Nationwide
  • Time-varying Cox analyses

Main finding

Incidence of ED

Adjusted hazard ratio

1.20

95% CI 1.12–1.28

T2Dvs General population
aHR 1.20 (95% CI 1.12–1.28)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Incidence of eating disorders (ED) by insulin use (vs general population)

Insulin users, aHR
1.30 [1.09, 1.54] (95% CI)
Non-insulin users, aHR
1.18 [1.11, 1.27] (95% CI)
  • Incidence of ED higher among insulin users than non-insulin users

Outcomes in T2D with ED

All-cause mortality, aHR
2.57 [2.30, 2.87] (95% CI)
Composite CVD, aHR
1.68 [1.44, 1.96] (95% CI)
Cardiovascular (CV)-related mortality, aHR
2.68 [1.94, 3.70] (95% CI)
CV-related hospitalisation, aHR
1.61 [1.37, 1.89] (95% CI)
  • Increased rates in the T2D with ED group

Original publication

High incidence of eating disorders in individuals with type 2 diabetes and their association with cardiovascular and mortality risks. Diabetologia. Published 26 November 2025. doi:10.1007/s00125-025-06615-z

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