Hepatic Steatosis and Cardiovascular Risk in Obesity: A 10‐Year Follow‐Up Study From Childhood Into Young Adulthood
Main finding · cIMT in adulthood by steatosisResult — go to the resultMean difference 0.035 mm 95% CI 0.010–0.060Authors' conclusion
Hepatic steatosis in young adulthood is independently associated with increased cardiovascular risk, and childhood steatosis relates to cIMT progression
Study context
- Population
- Children with severe obesity followed into young adulthood; steatosis by proton MR spectroscopy, cardiovascular risk by US carotid intima-media thickness (cIMT)
- Participants
- 52 children
- Exposure
- Hepatic steatosis vs no steatosis
- Outcome
- Carotid intima-media thickness (cIMT) in adulthood
- Follow-up
- 10-year follow-up
Methodological details10-year follow-up
- 10-year follow-up
Main finding
cIMT in adulthood by steatosis
Mean difference
0.035 mm
95% CI 0.010–0.060
p-adjusted = 0.008
Adulthood steatosisvs No adulthood steatosis
mean difference 0.035 mm (95% CI 0.010–0.060); p-adjusted = 0.008
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalence of steatosis
- Steatosis in childhood
- 46%
- Steatosis in adulthood
- 46%
Childhood metabolic factors and cIMT progression
- Childhood steatosis, the only metabolic factor associated with cIMT progression (β)
- 0.006, p = 0.030
Original publication
Hepatic Steatosis and Cardiovascular Risk in Obesity: A 10‐Year Follow‐Up Study From Childhood Into Young Adulthood. Pediatr Obes. Published 2 September 2026. doi:10.
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