Type 2 & other diabetes

Healthcare cost trajectories before and after incident cardiovascular disease in type 2 diabetes: A latent class analysis

Diabetes Res Clin PractPublished Retrospective cohort study with latent class analysis

Authors' conclusion

Baseline phenotypes in adults with T2D experiencing an incident CVD event were associated with longitudinal cost trajectories and age and sex differences.

Study context

Population
Chinese adults with T2D and incident cardiovascular disease (CVD), Hong Kong Diabetes Register (2007–2019)from 24,058 adults with T2D
Participants
1,098 adults
Exposure
Elderly, later-onset with good control vs Elderly women, usual-onset with poor control vs Middle-aged, younger-onset with poor control vs Elderly men, usual-onset with poor control
Outcome
Longitudinal annual healthcare costs before and after incident CVD event, by latent class
Methodological detailsmixed-effects models, population-based register
  • Mixed-effects models
  • Population-based register

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Within-class factors associated with costs

Anaemia, CKD and multimorbidity associated with higher costs
Regular physical activity associated with lower costs in older men

Original publication

Healthcare cost trajectories before and after incident cardiovascular disease in type 2 diabetes: A latent class analysis. Diabetes Res Clin Pract. Published 13 July 2026. doi:10.1016/j.diabres.2026.113433

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