Type 2 & other diabetes

Compositional analyses of accelerometer-measured 24-h movement behaviors among adults with normoglycemia, pre-diabetes phenotypes, and diabetes: a population-based study

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

Notably, the associations with 24-h movement behaviors appeared to differ across distinct pre-diabetes phenotypes, providing preliminary evidence for precision prevention strategies.

Study context

Population
Adults from NHANES 2005–2006; glycemic status by ADA criteria; mean age 41.02 (SD = 12.97) years, 47.22% males
Participants
1,222 adults
Exposure
24-h movement behaviors across glycemic status
Outcome
Associations of accelerometer-measured SB, LIPA, MVPA and self-reported sleep with pre-diabetes phenotypes and diabetes, adjusted for age, sex, education and smoking
Methodological detailspopulation-based, compositional data analysis
  • Population-based
  • Compositional data analysis

Main finding

As reported in the abstract

Association of 24-h movement behaviors with pre-diabetes phenotypes and diabetes
Each group vs normoglycemiaOdds ratio (95% CI)P value
i-IGTSB
3.49(1.10–11.09)
P = 0.038
IFG + IGTMVPA
0.57(0.45–0.71)
P < 0.001
Diabetessleep
0.47(0.25–0.88)
P = 0.025
DiabetesMVPA
0.55(0.39–0.77)
P = 0.005
DiabetesSB
2.33(1.07–5.08)
P = 0.037
None of the four movement behaviors was associated with i-IFG
all p > 0.05

Observational data: associations, not effects.

Further findings

Mean daily time in movement behaviors

h

Sleep
6.8
Sedentary behavior (SB)
9.4
Light-intensity physical activity (LIPA)
7.3
Moderate-to-vigorous physical activity (MVPA)
0.5

Original publication

Compositional analyses of accelerometer-measured 24-h movement behaviors among adults with normoglycemia, pre-diabetes phenotypes, and diabetes: a population-based study. Int J Obes (Lond). Published 13 July 2026. doi:10.1038/s41366-026-02162-8

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