Compositional analyses of accelerometer-measured 24-h movement behaviors among adults with normoglycemia, pre-diabetes phenotypes, and diabetes: a population-based study
Authors' conclusion
Notably, the associations with 24-h movement behaviors appeared to differ across distinct pre-diabetes phenotypes, providing preliminary evidence for precision prevention strategies.
Study context
- Population
- Adults from NHANES 2005–2006; glycemic status by ADA criteria; mean age 41.02 (SD = 12.97) years, 47.22% males
- Participants
- 1,222 adults
- Exposure
- 24-h movement behaviors across glycemic status
- Outcome
- Associations of accelerometer-measured SB, LIPA, MVPA and self-reported sleep with pre-diabetes phenotypes and diabetes, adjusted for age, sex, education and smoking
Methodological detailspopulation-based, compositional data analysis
- Population-based
- Compositional data analysis
Main finding
As reported in the abstract
Association of 24-h movement behaviors with pre-diabetes phenotypes and diabetes
Each group vs normoglycemiaOdds ratio (95% CI)P value
i-IGTSB
3.49(1.10–11.09)
P = 0.038IFG + IGTMVPA
0.57(0.45–0.71)
P < 0.001Diabetessleep
0.47(0.25–0.88)
P = 0.025DiabetesMVPA
0.55(0.39–0.77)
P = 0.005DiabetesSB
2.33(1.07–5.08)
P = 0.037- None of the four movement behaviors was associated with i-IFG
- all p > 0.05
Observational data: associations, not effects.
Further findings
Mean daily time in movement behaviors
h
- Sleep
- 6.8
- Sedentary behavior (SB)
- 9.4
- Light-intensity physical activity (LIPA)
- 7.3
- Moderate-to-vigorous physical activity (MVPA)
- 0.5
Original publication
Compositional analyses of accelerometer-measured 24-h movement behaviors among adults with normoglycemia, pre-diabetes phenotypes, and diabetes: a population-based study. Int J Obes (Lond). Published 13 July 2026. doi:10. 1038/ s41366-026-02162-8
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