Health state utility values for children and adolescents with type 1 diabetes: A systematic review and meta‐analysis
Authors' conclusion
This study developed a reference set of pooled utility estimates for children and adolescents with T1DM, which is helpful for understanding the overall health status of T1DM and conducting economic evaluations. Further studies are needed to explore the utilities of T1DM with different types of complications.
Study context
- Population
- Children and adolescents (aged ≤18 years) with T1D; health utility values measured by direct and indirect preference elicitation; MEDLINE and Embase to March 2023
- Participants
- 1,276 children6 studies
- Outcome
- Pooled health utility value
Methodological detailssubgroup analyses by populations and elicitation approaches
- Subgroup analyses by populations and elicitation approaches
Pooled result
As reported in the abstract
Overall pooled utility value
Overall utility value, children and adolescents with T1D
0.91
95% CI 0.89–0.93
Further pooled results
| Outcome | Values |
|---|---|
| Utility value by age | Children (aged <13 years) 0.90 · Adolescents (aged 13-18 years) 0.85 |
| Utility value by elicitation instrument | EQ-5D-3L 0.91 · HUI3 0.89 · SF-6Dv1 0.83 · Time trade-off 0.81 |
| Utility value by reporter | Parent proxy-reported 0.91 · Patient self-reported 0.91 |
Value
With complications
0.90(95% CI 0.88–0.92)
Without complications
0.96(95% CI 0.95–0.97)
- Lower with complications than without
Utility value by age
- Higher in children than adolescents
Utility value by elicitation instrument
- EQ-5D-3L higher than HUI3, SF-6Dv1 and time trade-off
Utility value by reporter
- Parent proxy-reported similar to patient self-reported
Original publication
Health state utility values for children and adolescents with type 1 diabetes: A systematic review and meta‐analysis. Diabet Med. Published 8 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →