Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non‐Hispanic White individuals
Authors' conclusion
Higher HCC was associated with greater adiposity in late adolescence. Further research is needed to disentangle the relationship between HCC and adolescent adiposity, including the temporal direction of the relationship and sex-specific associations.
Study context
- Population
- Non-Hispanic White adolescents in Project Viva; 48.5% female, mean age 17.7 years
- Participants
- 336 adolescents
- Exposure
- Higher vs lower hair cortisol concentration (HCC)
- Outcome
- Associations of HCC with adiposity: BMI, BIA % body fat, waist circumference, DXA % and total fat or trunk fat mass
Methodological detailsmultivariable linear regression, sex-stratified analyses, adjusted for age and known predictors of adiposity
- Multivariable linear regression
- Sex-stratified analyses
- Adjusted for age and known predictors of adiposity
Main finding
As reported in the abstract
Adiposity per doubling of HCC (adjusted)
- Body mass index (BMI) per doubling of HCC, β
- 0.19 kg/m² (95% CI 0.00, 0.37)
- Bioelectric impedance (BIA) % body fat per doubling of HCC, β
- 0.41% (95% CI 0.04, 0.77)
- Effect modification by sex
- no evidence
- HCC, median (IQR 1.0-4.5)
- 2.1 pm/mg
- BMI, mean (SD 3.9)
- 23.1 kg/m²
- BIA % body fat, mean (SD 9.9)
- 20.2%
- Waist circumference (WC), mean (SD 10.9)
- 80.6 cm
Observational data: associations, not effects.
Original publication
Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non‐Hispanic White individuals. Pediatr Obes. Published 19 August 2024. doi:10.
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